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Research News
Ketamine Elicits Brain State Resembling Early Stages of Schizophrenia
26 August 2014. Blocking glutamate receptors with ketamine produces a state of hyperconnectivity in the prefrontal cortex that most resembles that found in early stages of schizophrenia...
SIRS 2014—Connecting Clinical and Preclinical Research
22 August 2014. The April 7 SIRS 2014 plenary session focused on three aspects of schizophrenia symptoms: psychosis, motivation, and social cognition...
Stem Cells and TALENs Bring DISC1 Back in the News
18 August 2014. DISC1 returns to center stage, thanks to a marriage of stem cell and DNA editing technologies...

DISC1 iPS Cell Paper Evokes Discussion
The recent publication in Nature of a paper describing induced pluripotent stem cells from mental illness patients who have mutations in the gene DISC1 has generated interest. Read comments by Kristen Brennand, Carsten Korth, Nick Brandon, and Atsushi Kamiya, and contribute your own thoughts.
Schizophrenia Researchers Convene at SIRS Meeting
Some 1,600 researchers and clinicians gathered amidst the public art of Florence, Italy, to discuss the latest in schizophrenia research at the Schizophrenia International Research Society Conference (SIRS) meeting. Discussions ranged from possible links between psychosis and different types
of infections to broadening the definition of "schizophrenia." We have now posted all of our reports from these sessions. Image courtesy of Wikimedia See also Allison Curley's photos from the Firenze Fiera Congress Center.
Drugs in Trials Compendium Updated
Hugo Geerts
This week, Hugo Geerts weighs in with his semiannual update on clinical trials for schizophrenia. Amid many disappointing results, there are a few compounds that have made progress: Intra-Cellular Therapeutics's ITI-007 and Reviva's RP5063, both of which have dopaminergic as well as serotonergic targets and had successful Phase 2 proof-of-concept trials. Other updates are for EGIS-11150, BFF-816, AZD2624, Org25925, F17464, F17807, AE58054, MP-10, bitopertin, TC5619, DAR-100, NW3509, and AUT6.
Welcome to the Schizophrenia Research Forum!
Welcome to the Schizophrenia Research Forum website—a virtual community for science about schizophrenia and related disorders. Our Mission is to help researchers in their quest for causes, improved treatments, and better understanding of schizophrenia. Read more about ways to browse the site.
What's New

Comments - Posted 26 August 2014
Read remarks by Hugo Geerts about Anticevic A et al.
NEWS: Ketamine Elicits Brain State Resembling Early Stages of Schizophrenia
Comments - Posted 26 August 2014
Read remarks by Alexandre Seillier about Metaxas A et al.
PAPER: Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels.
Comments - Posted 25 August 2014
Read remarks by Atsushi Kamiya about Wen Z et al.
NEWS: Stem Cells and TALENs Bring DISC1 Back in the News
Conferences - Posted 24 August 2014
Winter Conference on Brain Research: 24-29 January 2015, Big Sky, MT, U.S.A.
Comments - Posted 22 August 2014
Read remarks by Barbara K. Lipska about Jan-Harry Cabungcal et al.
NEWS: Model of Schizophrenia Cortical Deficits Reversed With Antioxidants
Jobs - Posted 19 August 2014
Junior Faculty Position in Vision Research in Schizophrenia: Rutgers Biomedical and Health Sciences, Piscataway, New Jersey.
August 27, 2014
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