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Common Pathways Found for Some Psychiatric Disorders
29 January 2015. Diverse genetic clues associated with three psychiatric disorders, including schizophrenia, point to a subset of key biological processes...
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Elusive Hybrid Dopamine Receptor Stirs Controversy
15 January 2015. The hybrid dopamine receptor consisting of D1 and D2 subunits may not matter much to normal brain function...
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SfN 2014—Redox Dysregulation in Schizophrenia
13 January 2015. Data suggest that redox dysregulation interacts with glutamatergic dysfunction and neuroinflammation to cause cognitive and affective symptoms of schizophrenia...
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Spotlight
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Elusive Hybrid Dopamine Receptor Stirs Controversy
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 D2 Receptor awaiting its D1 mate? |
One would think that the illustrious dopamine D2 receptor would be understood in exhaustive detail at this point, but, in fact, there is much about it that remains to be determined. (As far as we know, there isn't even an experimentally derived crystal image, leaving us with the broad cartoon we show here.) A case in point is the D1/D2 receptor heteromer postulated by Susan George and colleagues at the University of Toronto. In a new paper online in Molecular |
Psychiatry, Gregg Stanwood of Vanderbilt University and Jonathan Javitch of Columbia University suggest that it is illusory, at least in terms of physiological relevance to psychiatric disorders. Read Michele Solis' news story and George's initial reaction to the new paper. We invite you to join the discussion and let us know which argument persuades you and why....
Image: "Protein DRD2 PDB 1I15" by Pleiotrope. Own work. Licensed under Public Domain via Wikimedia Commons
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SfN Meeting Draws Researchers to Washington
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 The Lincoln Memorial |
The Society for Neuroscience's annual meeting drew more than 30,000 to Washington, DC, from November 15 to 19. Over the next several weeks, keep an eye out for reports from the meeting by SRF reporter Allison Marin, beginning with a discussion of an issue that has created consternation throughout science: the |
difficulty of replicating research, even the seminal studies in many fields.
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Welcome to the Schizophrenia Research Forum!
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Welcome to the Schizophrenia Research Forum website—a virtual community for science about schizophrenia and related disorders. Our Mission is to help researchers in their quest for causes, improved treatments, and better understanding of schizophrenia. Read more about ways to browse the site.
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What's New
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Jobs - Posted 29 January 2015
Research Associate: Imperial College London, Institute of Clinical Sciences, London, UK. |
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Conferences - Posted 29 January 2015
The Neuropsychopathology of Schizophrenia: 9-10 April 2015, University of Nebraska–Lincoln, Lincoln, Nebraska, U.S.A. |
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Comments - Posted 29 January 2015
Read remarks by Alexander B. Niculescu about
The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal et al.
NEWS: Common Pathways Found for Some Psychiatric Disorders |
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Comments - Posted 29 January 2015
Read remarks by Irving Gottesman about Birnbaum R et al.
PAPER: Investigation of the Prenatal Expression Patterns of 108 Schizophrenia-Associated Genetic Loci. |
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Comments - Posted 22 January 2015
Read remarks by Bryan Roth about
Frederick AL et al.
NEWS: Elusive Hybrid Dopamine Receptor Stirs Controversy |
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Comments - Posted 20 January 2015
Read remarks by Richard Mailman about
Frederick AL et al.
NEWS: Elusive Hybrid Dopamine Receptor Stirs Controversy |
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January 31, 2015 |
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 SRF News
SRF Comments
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 See our latest webinar, Cognition and Treatment Resistance in Schizophrenia, held November 10, 2014.
See our last webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.
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New Schizophrenia Fact Sheet for Patients and Families
Latest BBRF Research Breakthroughs
Visit our Facebook page and our Blog.
Support the Brain & Behavior Research Foundation Today.
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15th International Congress on Schizophrenia Research
March 28-April 01, 2015
The Broadmoor
Colorado Springs, Colorado, US
Abstract submission deadline extended: October 13, 2014, 5:00 p.m. EST
Early registration: July-December 2014
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SZGene
AlzGene
MSGene
PDGene
An up-to-date collection of all published genetic association studies.
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A community resource created by Jim Koenig, University of Maryland.
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We invite your comments and suggested edits to these facts about schizophrenia.
Compiled by Angus MacDonald, S. Charles Schulz, and the Minnesota Consensus Group.
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Replication in the Vicinity of Absolute Blocks to Replication: Tuesday, January 20, 2015, 12:30 p.m.
National Advisory Neurological Disorders and Stroke Council Meeting—January 2015: Thursday, January 29, 2015, 8:00 a.m.
The Generation of Cortical interneuron Diversity: Both Nurture and Nature: Monday, February 02, 2015, 12:00 p.m.
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Research Participants
Collaborators
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