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Printable version  
Meta-Analysis of All Published Schizophrenia-Association Studies
 (Case-Control Only) rs1800532
Back Search Methods Disclaimer Credits
 Polymorphism: rs1800532 (218A/C)
 Gene: TPH1  (TPH; TPRH)  Entrez Gene    View on AlzGene
 Protein: tryptophan hydroxylase 1  (tryptophan 5-monooxygenase)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 28 January 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   A-Allele
(frequency)		 C-Allele
(frequency)		 A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian 2 SZ
CTR		 0.42
0.38		 0.58
0.63		 193 (0.186)
251 (0.136)		 493 (0.474)
882 (0.478)		 354 (0.340)
711 (0.386)
 Asian 5 SZ
CTR		 0.52
0.48		 0.48
0.52		 291 (0.280)
324 (0.230)		 497 (0.478)
714 (0.506)		 251 (0.242)
372 (0.264)
Total 7 SZ
CTR		 0.47
0.42		 0.53
0.58		 484 (0.233)
575 (0.177)		 990 (0.476)
1596 (0.490)		 605 (0.291)
1083 (0.333)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1800532 (218A/C)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs10488683
rs10741734
rs211102
rs211105
rs4537731
rs684302
rs7933505
rs9633898
TPH1_5pb-Indel (GTTTT4/5)
TPH1_-6526A/G
TPH1_-7065C/T
TPH1_-7180G/T
TPH1_IVS7nt13
TPH1_SNP (intron7/HaeIII)

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