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	Recent Updates Current Papers Search All Papers Search Comments Research News Current Hypotheses Idea Lab Online Discussions Virtual Conferences Interviews What We Know SchizophreniaGene Animal Models Drugs in Trials Research Tools Grants Jobs Conferences Journals Community Calendar General Information Member Directory Researcher Profiles Institutes and Labs Mission History SRF Team Advisory Board Support Us How to Cite Fan (E)Mail The Schizophrenia Research Forum web site is sponsored by NARSAD, the Mental Health Research Association, and supported in part by a contract from the National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services		Overview of all published large-scale and genome-wide association studies in SZ  Status: Updated 27 February 2010;  ** See Large Scale Study Methods ** GWAS (genome-wide association studies)               SZ Cases Normal Controls     Study Design Type Population Source Platform # of SNPs Genotype Data Publicly Available DX # Subjects (GWAS) # Subjects (follow-up) # Subjects (GWAS) # Subjects (follow-up) Featured Genes Comment  Caucasian Athanasiu, 2010 * Recently Added * CC GWAS Norway (TOP), Europe (SGENE-plus) CL Affymetrix 6.0 572,888 No M 201 2663 305 13780 ACSM1 ANK3 PLAA ISC, 2009 CC GWAS, and meta-analysis (ISC, MGS, SGENE) Europe (ISC) CL Affymetrix 500K, 5.0, 6.0 739,995 No M 3322 - 3587 - GWA_6p22.1 MYO18B NOTCH4 RPP21 Kirov, 2008 FBAT GWAS Bulgaria CL Illumina HumanHap (550K) 433680 No IV 574 - 1753 - CCDC60 RBP1 Lencz, 2007 CC GWAS USA CL Affymetrix (500K) 439511 No IV 178 - 144 - CSF2RA IL3RA Mah, 2006 CC GWAS USA CL Selected cSNPs 25494 No IV 320 - 325 - PLXNA2 Need, 2009 CC GWAS (multi-stage) Mixed CL Illumina HumanHap (300,550K) 312,565 No M 871 1460 863 12995   Shifman, 2008 CC GWAS (multi-stage) Israel CL Affymetrix (500K) 510552 No IV 660 - 2771 - RELN Stefansson, 2009 CC GWAS, and meta-analysis (ISC, MGS, SGENE) Europe (SGENE-plus) CL Illumina HumanHap (300,550K) 314,868 No M 2663 4999 13498 15555 HIST1H2BJ NOTCH4 NRGN PGBD1 PRSS16 TCF4  Other/Mixed O'Donovan, 2008 CC GWAS (multi-stage) Mixed CL Affymetrix (500K) 362,532 No IV 7308 - 12834 - GWA_11p14.1 GWA_16p13.12 ZNF804A Shi, 2009 CC GWAS, and meta-analysis (ISC, MGS, SGENE) USA (MGS) CL,PO Affymetrix 6.0 696,788-843,798 Yes M 3967 - 3626 - AGAP1 ERBB4 GWA_6p22.1 HIST1H2AH HIST1H2BJ POM121L2 Sullivan, 2008 CC GWAS USA (CATIE) CL Affymetrix (500K) & Perlegen (customized) 492900 Yes IV 738 - 733 -   Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details. Other large-scale studies               SZ Cases Normal Controls     Study Design Type Population Source Platform # of SNPs Genotype Data Publicly Available DX # Subjects (GWAS) # Subjects (follow-up) # Subjects (GWAS) # Subjects (follow-up) Featured Genes Comment  Caucasian Christoforou, 2007 CC Fine-mapping (4p15-16) UK (Scotland) CL Illumina (customized) 408 Yes IV 386 - 458 - 4p15-16_D2 4p15-16_D7 O'Dushlaine, 2010 * Recently Added * CC GWAS re-analysis (pathways) Mixed (ISC, GAIN) CL see primary studies see primary studies No U 3322 1351 3587 1378 PATHWAY1  Asian Koga, 2009 CC Other (chromatin remodeling pathway analysis) Japan CL Illumina (109k, HumanHap370) 11,883 No IV 100 1920 740 1920 SMARCA2 Liu, 2009 CC GWAS (STR screen, pooled) China CL ABI (PRISM Linkage Mapping Set MD-10) 400 No IV 119 190 119 190 JARID2 Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details. Design: “CC” (case-control), “FBAT” (family-based) Type: “GWAS” (genome-wide association study); “CWA” (chromosome-wide association study); “LSA” (other large-scale association study); “cSNP” (coding-region SNP) Source: Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based). Platform: Please refer to orignal publication for exact description. # SNPs: Approximate number of polymorphisms covered. DX: Criteria used to determine SZ diagnosis -> "IIIR" (DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown). Featured Genes: Dropdown menu of genes highlighted (“featured”) in original publication as potential SZ susceptibility genes/loci after completion of all analyses, e.g. replication in multiple samples. (-) : No information provided/not applicable.
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