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	Recent Updates Current Papers Search All Papers Search Comments Research News Current Hypotheses Idea Lab Online Discussions Virtual Conferences Interviews What We Know SchizophreniaGene Animal Models Drugs in Trials Research Tools Grants Jobs Conferences Journals General Information Member Directory Researcher Profiles Institutes and Labs Mission History SRF Team Advisory Board Support Us How to Cite The Schizophrenia Research Forum web site is sponsored by NARSAD, the Mental Health Research Association, and supported in part by a contract from the National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services		Overview of all published large-scale and genome-wide association studies in SZ  Status: Updated 4 June 2008;  ** See Large Scale Study Methods ** Overview of all published large-scale and genome-wide association studies in SZ               SZ Cases Normal Controls     Study Design Type Population Source Platform # of SNPs Genotype Data Publicly Available # Subjects (% women) DX Onset Age (range) Age (range) # Subjects (% women) Age (range) Featured Genes Comment  Caucasian Christoforou, 2007 CC Fine-mapping (4p15-16) UK (Scotland) CL Illumina (customized) 408 Yes 386 (28%) IV - - 458 (48%) - 4p15-16_D2 4p15-16_D7 Kirov, 2008 FBAT GWA Bulgaria CL Illumina (HumanHap 550) 433680 No 574 (-) IV - - 1753 (-) - CCDC60 RBP1 Lencz, 2007 CC GWA USA CL Affymetrix (500K) 439511 No 178 (37%) IV - - 144 (44%) - CSF2RA IL3RA Mah, 2006 CC GWA USA CL Selected cSNPs 25494 No 320 (34%) IV - 46 (-) 325 (-) - PLXNA2 Shifman, 2008 CC GWA (multi-stage) Israel CL Affymetrix (500K) 510552 No 660 (37%) IV - - 2771 (35%) - RELN  Other/Mixed Sullivan, 2008 CC GWA USA (CATIE) CL Affymetrix (500K) & Perlegen (customized) 492900 Yes 738 (26%) IV - 40.9 + 11.1 (-) 733 (33%) 41 + 11.6 (-)   Use our Contact Form to alert us of discrepancies, errors in the representation of study details, or to notify us of your association study regarding this gene. Design:  “CC” (case-control), “FBAT” (family-based) Type:  “GWA” (genome-wide association study); “CWA” (chromosome-wide association study); “LSA” (other large-scale association study); “cSNP” (coding-region SNP) Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based). Platform:  Please refer to orignal publication for exact description. # SNPs:  Approximate number of polymorphisms covered. Onset Age and Age:  Mean or median age at onset or examination, respectively. DX:  Criteria used to determine SZ diagnosis -> "C" (clinical SZ diagnosis), "N" (neuropathological SZ diagnosis), "M" (mixed, i.e. SZ sample contains both clinical and neuropathological cases), "U" (unknown). Featured Genes:  Dropdown menu of genes highlighted (“featured”) in original publication as potential SZ susceptibility genes/loci after completion of all analyses, e.g. replication in multiple samples. (-) :  No information provided.
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