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Printable version  
Gene Overview of All Published Schizophrenia-Association Studies for PPIL2     
Back Search Methods Disclaimer Credits
 Gene: PPIL2  (CYC4; CYP60; hCyP-60)  Entrez Gene    View on AlzGene
 Protein: peptidylprolyl isomerase-like 2  (cyclophilin, 60kDa; cyclophilin-like protein CyP-60; peptidylprolyl cis-trans isomerase)  ProteinLink
 Chromosome: 22   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 28 January 2010
Meta-Analysis
1. Case-Control Studies (by ethnic group)
      SZ Cases Normal Controls    
Study Population Source # Polys # Subjects
(% women)
DX Onset Age
(range)
Age
(range)
# Subjects
(% women)
Age
(range)
Result Comment
 Caucasian
Horowitz, 2005
Israel (I) CL  1  (detail)  190
(41%)
U--188
(41%)
-Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
2. Family-Based Studies (by ethnic group)
      Affecteds Unaffecteds    
Study Population # Polys # Families # Subjects
(% women)
DX Onset Age
(range)
Age
(range)
# Subjects
(% women)
Age
(range)
Result Comment
 Caucasian
Takahashi, 2003
USA (II)  1  (detail)  3972
(31%)
IIIR-42.1 + 14.4
(-)
--Negative
 African Descent
Takahashi, 2003
USA (I)  1  (detail)  2966
(48%)
IIIR-38.7 + 11.1
(-)
--Negative
 Asian
Takahashi, 2003
China  1  (detail)  5258
(-)
IV----Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
# Polys:  Number of polymorphisms tested per gene and per sample.
Onset Age and Age:  Mean or median age at onset or examination, respectively.
DX:  Criteria used to determine SZ diagnosis ->  "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
(-) :  Either no data provided or in case of overlap, data included in original study.
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