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		Gene Overview of All Published Schizophrenia-Association Studies for DTNBP1
		Gene: DTNBP1  (SDY; DBND; HPS7; My031; FLJ30031; MGC20210)    Protein: dystrobrevin binding protein 1  (dysbindin)    Chromosome: 6   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)  Status: Updated 13 March 2010 1. Case-Control Studies (by ethnic group)       SZ Cases Normal Controls     Study Population Source # Polys # Subjects (% women) DX Onset Age (range) Age (range) # Subjects (% women) Age (range) Result Comment  Caucasian Bakker, 2006 Netherlands CL  4  (detail)  308 (-) IV - - 580 (-) - Negative Betcheva, 2009 Bulgaria (I) CL  13  (detail)  185 (-) IV - - 184 (-) - Trend Betcheva, 2009 Bulgaria (II) CL  1  (detail)  70 (-) IV - - 372 (-) - Negative Datta, 2007 UK CL  8  (detail)  450 (-) RDC - - 450 (-) - Negative Dutt, 2009 UK, Ireland CL  2  (detail)  83 (-) IV - - 57 (-) - Negative Dwyer, 2009 UK CL  7  (detail)  669 (32%) IV - - 710 (33%) - Negative Fallgatter, 2010 Germany CL  7  (detail)  44 (50%) IV - 36.3 + 9.6 (-) 48 (54%) 26.5 + 7.2 (19-63) n.a. Funke, 2004 USA (I) CL  6  (detail)  196 (-) IV - - 467 (52%) 39.3 (-) Positive Holliday, 2006 Australia CL  15  (detail)  194 (-) M - - 180 (-) - Negative Jonsson, 2009 Denmark, Norway, Sweden CL  11  (detail)  837 (42%) M 26.5 (-) 45.7 (-) 1473 (42%) 44.1 (-) Negative Li, 2005 UK (Scotland) CL  11  (detail)  580 (28%) M - - 620 (43%) - Negative Morris, 2003 Ireland CL  8  (detail)  219 (-) IIIR - - 231 (-) - Negative Morris, 2007 Overlaps with Morris, 2003 CL  2  (detail)  373 (-) IV - - 812 (-) - n.a. Morris, 2007 Overlaps with Williams, 2004 CL  1  (detail)  373 (-) IV - - 812 (-) - n.a. Pedrosa, 2006 USA (II) CL  1  (detail)  172 (-) M - - 165 (-) - Negative Peters, 2008 Australia CL  37  (detail)  336 (20%) M - - 172 (41%) - Negative Rethelyi, 2009 Hungary CL  4  (detail)  280 (54%) IV 28.6 (-) 37.6 (-) 230 (57%) 39.9 (-) Positive Riley, 2009 Ireland, UK CL  9  (detail)  1021 (32%) IIIR - - 626 (45%) - Positive Sanders, 2008 USA, Australia CL  38  (detail)  1870 (31%) IV - - 2002 (53%) - Negative Strohmaier, 2010 Germany CL  35  (detail)  634 (45%) IV - 38.5 + 11.7 (-) 776 (43%) 45.5 + 13.5 (-) Negative Tosato, 2007 Italy CO  11  (detail)  80 (49%) 10 - 42 (-) 106 (47%) 38 (-) Positive Van Den Bogaert, 2003 Overlaps with Strohmaier, 2010 (Germany) CL  5  (detail)  418 (52%) IV - - 285 (40%) - Negative Van Den Bogaert, 2003 Poland CL  5  (detail)  294 (41%) IV - - 113 (63%) - Negative Van Den Bogaert, 2003 Sweden CL  5  (detail)  142 (38%) IV - - 272 (45%) - Positive Vilella, 2007 Spain PO  11  (detail)  589 (31%) IV - - 615 (48%) - Positive Williams, 2004 Overlaps with Morris, 2003 CL  2  (detail)  219 (101%) IIIR 25.2 + 12.4 (-) 46 + 8.5 (-) 231 (-) - Positive Williams, 2004 UK, Ireland CL  20  (detail)  708 (31%) IV 23.6 + 7.7 (-) 41.8 + 13.5 (-) 711 (33%) - Positive Williams, 2004 Ireland (II) CL  1  (detail)  219 (-) IIIR 25.2 + 12.4 (-) 46 + 8.5 (-) 231 (-) - Positive Wood, 2006 USA CL  15  (detail)  311 (-) IV - - 291 (-) - Negative Zuo, 2009 USA (I) CL  6  (detail)  235 (-) IIIR - - 298 (-) - Positive  African Descent Funke, 2004 USA (II) CL  6  (detail)  184 (-) IV - - 74 (59%) 31.9 (-) Positive Pedrosa, 2006 USA (I) CL  1  (detail)  152 (-) M - - 129 (-) - Negative Zuo, 2009 USA (II) CL  6  (detail)  82 (-) IIIR - - 48 (-) - Trend  Asian Hashimoto, 2009 Japan CL  1  (detail)  70 (39%) IV 24.8 (-) 45.1 (-) 165 (67%) 37.3 (-) n.a. Joo, 2006 Korea CL  5  (detail)  194 (35%) IV 22.7 + 5.7 (-) 35 + 6.2 (-) 351 (50%) 25.9 + 6.4 (-) Negative Numakawa, 2004 Japan CL  6  (detail)  670 (49%) IV - 44.2 + 14.6 (-) 588 (51%) 36.2 + 12.4 (-) Positive Pae, 2009 Korea CL  4  (detail)  908 (49%) M - 33.7 (-) 601 (49%) 38.9 (-) Positive Tochigi, 2006 Japan CL  12  (detail)  314 (44%) IV - 46.3 + 14.9 (-) 314 (44%) 37.6 + 11.3 (-) Positive  Hispanic Funke, 2004 USA (III) CL  6  (detail)  41 (-) IV - - 32 (41%) 32.9 (-) Negative  Other/Mixed Pedrosa, 2006 USA (I+II) CL  3  (detail)  324 (-) M - - 294 (-) - Negative Zinkstok, 2007 Netherlands and Other CL  7  (detail)  76 (13%) IV - 21.5 + 2.9 (-) 31 (26%) 21.5 + 3.1 (-) Negative Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details. 2. Family-Based Studies (by ethnic group)       Affecteds Unaffecteds     Study Population # Polys # Families # Subjects (% women) DX Onset Age (range) Age (range) # Subjects (% women) Age (range) Result Comment  Caucasian Hall, 2004 South Africa  5  (detail)  233 - IV - - - - Negative Hall, 2004 USA  5  (detail)  210 - IV - - - - Negative Holliday, 2006 Australia  15  (detail)  41 114 (-) M - - 135 (-) - Negative Kirov, 2004 Bulgaria  8  (detail)  488 488 (48%) IV - 33.1 + 8.2 (-) 976 (50%) 59.9 + 9.2 (-) Positive Straub, 2002 Ireland  12  (detail)  270 - IIIR - - - - Positive Strohmaier, 2010 Overlaps with Schwab, 2003 (Germany)  35  (detail)  180 - IV - - - - Negative Turunen, 2007 Finland  17  (detail)  441 865 (39%) IV - - 999 (-) - Negative Van Den Oord, 2003 Ireland  14  (detail)  268 - IIIR - - - - Positive Wessman, 2009 Re-analysis of Turunen, 2007  15  (detail)  292 - IV - - - - n.a.  Asian Li, 2005 China  8  (detail)  638 810 (45%) M - - 620 (-) - Positive Liu, 2007 Taiwan  9  (detail)  693 1487 (39%) IV 22.9 + 6.8 (-) 36 + 9.6 (-) 1300 (52%) 55.7 + 15.4 (-) Negative Tang, 2003 China  7  (detail)  233 233 (44%) IIIR - 22.8 + 0.5 (-) 466 (50%) - Positive  Other/Mixed De Luca, 2005 Canada  3  (detail)  11 - IV - - - - Trend Duan, 2007 USA  26  (detail)  136 319 (-) IIIR - - 463 (-) - Positive Fallin, 2005 USA  16  (detail)  263 274 (26%) IV 19.5 + 4.5 (-) - 548 (50%) - Positive Holliday, 2006 India  15  (detail)  197 329 (-) M - - 339 (-) - Negative Schwab, 2003 Mixed  6  (detail)  203 281 (-) IV - - - - Positive Zinkstok, 2007 Overlaps with Zinkstok, 2007  7  (detail)    76 (13%) IV - 21.5 + 2.9 (-) 31 (58%) 22.8 + 3.8 (-) n.a. Zinkstok, 2007 Netherlands and Other  7  (detail)  52 52 (-) IV - - - - Negative Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details. Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based). # Polys:  Number of polymorphisms tested per gene and per sample. Onset Age and Age:  Mean or median age at onset or examination, respectively. DX:  Criteria used to determine SZ diagnosis ->  "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown). Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between). (-) :  Either no data provided or in case of overlap, data included in original study.