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Drugs In Clinical Trials

Important Notice: The Forum does not endorse any medical product or therapy. ALL medications and supplements should be taken ONLY under the supervision of a physician, due to the possibility of side-effects, drug interactions, etc.

Drug: Reboxetine
Clinical Trial ID: NCT00409201
Mode of action: Norepineprhine transport inhibitor
Phase: POC Completed
Company:
Note: One positive and one negative study; also beneficial effect on weight gain

Useful Links:

Poyurovsky M, Fuchs C, Pashinian A, Levi A, Faragian S, Maayan R, Gil-Ad I. Attenuating effect of reboxetine on appetite and weight gain in olanzapine-treated schizophrenia patients: a double-blind placebo-controlled study. Psychopharmacology (Berl) . 2007 Jun ; 192(3):441-8. Abstract

Thomsen M, W├Ârtwein G, Fink-Jensen A, Woldbye DP, Wess J, Caine SB. Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice. Psychopharmacology (Berl) . 2007 May 1 ; 192(1):97-110. Abstract

Raedler TJ, Jahn H, Arlt J, Kiefer F, Schick M, Naber D, Wiedemann K. Adjunctive use of reboxetine in schizophrenia. Eur Psychiatry . 2004 Sep 1 ; 19(6):366-9. Abstract


October 23, 2014
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