Schizophrenia Research Forum: Drugs in Trials
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Drugs in Trials:GABA
Drug Development status Clinical Trial ID Company or Institution Mechanism Notes
Adidiplon Discontinued   Neurogen GABA a3 partial agonist Development in insomnia
L-830982 POC Completed   University of Pittsburgh GABA α2/3 agonist Add-on for cognitive disorders; in development for general anxiety disorders
PW4123 Inactive   PennWest CNS modulator Also in development for epilepsy, formulation approach
Tiagabine POC Ongoing NCT00179465 Beth Israel Deaconess Medical Center GABA enhancer Add-on
Valproate Inactive   Beijing Anding Hospital, Capital University of Medical Sciences Ion-channel modulator Add-on therapy; no effect on stable and partial responsive schizophrenia patients