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Animal Models

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Animal Model: Neuregulin-1 Heterozygous Knockout Of EGF-Like Domain Mice
Preparation Type: Genetic Preparations
DA-related behavior: Hyperactive in open field (Duffy; not replicated by Ehrlichman or Moy); normal exploratory behavior
Gating: No PPI deficit
Cognitive behavior: Normal novel object exploration
Social behavior: Decreased social interaction (Ehrlichman; increased sociability but decreased social novelty preference found by Moy)


November 25, 2014
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See our latest webinar, Cognition and Treatment Resistance in Schizophrenia, held November 10, 2014.

See our last webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.
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