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Animal Models

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Animal Model: Urokinase Plasminogen Activator Receptor KO (Plaur Mice)
Preparation Type: Genetic Preparations
Cognitive behavior: Impaired reversal learning
Molecular/morphological signature: Reduced parvalbumin-positive interneurons in anterior cingulate and orbitofrontal cortex; reduced levels of HGF/SF
Response to APD: Postnatal supplementation with HGF/SF normalizes reversal learning impairment


May 21, 2013
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See our most recent Schizophrenia Bulletin theme Webinar: Taking Stock of Glutamate in Schizophrenia, held 5 February 2013.

Check out our Schizophrenia Bulletin theme Webinar: Neurotropic Infectious Agents and Cognitive Impairment in Schizophrenia, held 13 November 2012.
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