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Important Notice: The Forum does not endorse any medical
product or therapy. ALL medications and supplements
should be taken ONLY under the supervision of a physician,
due to the possibility of side-effects, drug interactions,
etc.
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Animal Model:
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PACAP KO Mice
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Preparation Type:
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Genetic Preparations
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DA-related behavior:
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Hyperactive in open field
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Gating:
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PPI deficit
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Social behavior:
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Reduced social interaction
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Response to APD:
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Hyperactivity reduced with risperidone; PPI deficit reversed
by risperidone; social interaction deficit and hyperactivity
reduced when animals raised in enriched environment
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