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Animal Models

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Animal Model: Beta-arrestin 2 KO
Preparation Type: Genetic Preparations
DA-related behavior: Decreased locomotor response to amphetamine
Molecular/morphological signature: Normal DARRPP-32 phosphorylation after amphetamine
Citations: Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell . 2005 Jul 29 ; 122(2):261-73. Abstract


May 24, 2013
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See our most recent Schizophrenia Bulletin theme Webinar: Taking Stock of Glutamate in Schizophrenia, held 5 February 2013.

Check out our Schizophrenia Bulletin theme Webinar: Neurotropic Infectious Agents and Cognitive Impairment in Schizophrenia, held 13 November 2012.
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