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product or therapy. ALL medications and supplements
should be taken ONLY under the supervision of a physician,
due to the possibility of side-effects, drug interactions,
etc.
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Animal Model:
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Vasopressin 1b receptor KO
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Preparation Type:
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Genetic Preparations
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DA-related behavior:
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Reduced PFC DA
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Gating:
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Disrupted PPI
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Cognitive behavior:
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Impaired novel object recognition
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Social behavior:
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Decreased social interest; decreased social novelty
preference; Impaired social recognition
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Response to APD:
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Atypical APD improve PPI but not haloperidol
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Citations:
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Wersinger SR, Ginns EI, O'Carroll AM, Lolait SJ, Young WS.
Vasopressin V1b receptor knockout reduces aggressive
behavior in male mice. Mol Psychiatry . 2002 Jan 1 ;
7(9):975-84. Abstract
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