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Animal Model:
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Trace Amine 1 Receptor KO
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Preparation Type:
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Genetic Preparations
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DA-related behavior:
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Enhanced locomotor response to amphetamine
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Gating:
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Disrupted PPI
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Molecular/morphological signature:
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Increased psychostimulant-induced DA release
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Citations:
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Wolinsky TD, Swanson CJ, Smith KE, Zhong H, Borowsky B,
Seeman P, Branchek T, Gerald CP. The Trace Amine 1 receptor
knockout mouse: an animal model with relevance to
schizophrenia. Genes Brain Behav . 2007 Oct 1 ; 6(7):628-39.
Abstract
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