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Animal Models

Important Notice: The Forum does not endorse any medical product or therapy. ALL medications and supplements should be taken ONLY under the supervision of a physician, due to the possibility of side-effects, drug interactions, etc.

Animal Model: SNAP 25 Mutant
Preparation Type: Genetic Preparations
DA-related behavior: Deficit in exploratory behavior
Gating: PPI deficit
Social behavior: No social interaction deficit
Citations: Jeans AF, Oliver PL, Johnson R, Capogna M, Vikman J, Molnar Z, Babbs A, Partridge CJ, Salehi A, Bengtsson M, Eliasson L, Rorsman P, Davies KE. A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2431-6. Abstract


December 22, 2014
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See our latest webinar, Cognition and Treatment Resistance in Schizophrenia, held November 10, 2014.

See our last webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.
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