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Animal Models

Important Notice: The Forum does not endorse any medical product or therapy. ALL medications and supplements should be taken ONLY under the supervision of a physician, due to the possibility of side-effects, drug interactions, etc.

Animal Model: PLC-beta1 KO
Preparation Type: Genetic Preparations
DA-related behavior: Hyperactive
Gating: Sensorimotor gating deficits
Cognitive behavior: Memory impairment and lack of acquisition on hippocampal-dependent fear conditioning task
Social behavior: Abnormal social behavior
Response to APD: Clozapine (McOmish) and haloperidol (Koh) rescues sensorimotor deficits


May 20, 2013
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See our most recent Schizophrenia Bulletin theme Webinar: Taking Stock of Glutamate in Schizophrenia, held 5 February 2013.

Check out our Schizophrenia Bulletin theme Webinar: Neurotropic Infectious Agents and Cognitive Impairment in Schizophrenia, held 13 November 2012.
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