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Animal Models

Important Notice: The Forum does not endorse any medical product or therapy. ALL medications and supplements should be taken ONLY under the supervision of a physician, due to the possibility of side-effects, drug interactions, etc.

Animal Model: NCAM-180 KO
Preparation Type: Genetic Preparations
Gating: Disrupted PPI, no changes induced by apomorphine Rx
Response to APD: Increase lateral ventricle size
Citations: Wood GK, Tomasiewicz H, Rutishauser U, Magnuson T, Quirion R, Rochford J, Srivastava LK. NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle. Neuroreport . 1998 Feb 16 ; 9(3):461-6. Abstract


May 20, 2013
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See our most recent Schizophrenia Bulletin theme Webinar: Taking Stock of Glutamate in Schizophrenia, held 5 February 2013.

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