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Animal Models

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Animal Model: GSK-3beta Knockout
Preparation Type: Genetic Preparations
Gating: Disrupted PPI correlates with enzyme activity; no PPI disruption (Bersudsky)
Citations: Amar S, Jones BC, Nadri C, Kozlovsky N, Belmaker RH, Agam G. Genetic correlational analysis of glycogen synthase kinase-3 beta and prepulse inhibition in inbred mice. Genes Brain Behav . 2004 Jun 1 ; 3(3):178-80. Abstract

Bersudsky Y, Shaldubina A, Kozlovsky N, Woodgett JR, Agam G, Belmaker RH. Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behav Pharmacol. 2008 May; 19(3):217-24. Abstract

October 9, 2015
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