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Animal Model:
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Grin1D481N
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Preparation Type:
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Genetic Preparations
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Gating:
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Persistent latent inhibition
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Cognitive behavior:
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Spatial recognition impairments
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Social behavior:
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Social approach deficits
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Molecular/morphological signature:
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Reduced NMDAR glycine affinity
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Response to APD:
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Phenotype reversed by D-serine treatment
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