Animal Model:	Rodent Prenatal Immune Challenge: PolyI:C (delivery timing varies)
Preparation Type:	Developmental Preparations
DA-related behavior:	No change in total distance traveled in open field but reduced center exploration; increased response to amphetamine and MK-801 (emerges after puberty)--not rescued by cross-fostering
Gating:	Disrupted PPI and changes in latent inhibition (post-puberty); PPI deficit not rescued by cross-fostering
Cognitive behavior:	Reduced escape latency in Morris water maze; impairment n novel object recognition memory and latent inhibition (post-puberty); classical fear conditioning, active avoidance and discrimination learning appear normal
Social behavior:	Reduced social interaction
Molecular/morphological signature:	Amphetamine-induced DA release increased; increased hippocampal pyknotic cells; increased DA turnover and reduced binding to D2 receptors in striatum; reduced reelin- and parvalbumin- expressing neurons in PFC; reduced D1 receptors in PFC; increased TH expression in striatum; reduced density of cerebellar Purkinje cells; delayed myelination of hippocampus
Response to APD:	Deficits in latent inhibition and novel object recognition memory are improved by clozapine but not haloperidol