Animal Model:	Rat Prenatal Immune Challenge: LPS
Preparation Type:	Developmental Preparations
DA-related behavior:	Increased amphetamine-induced locomotion
Gating:	Enhanced acoustic startle; disrupted PPI (worse in males)
Cognitive behavior:	Impaired object recognition (post-puberty)
Social behavior:	Reduced social interaction, possibly due to increased anxiety
Molecular/morphological signature:	Reduced dendritic complexity in PFC and hippocampus; increased accumbal DA and striatal DOPAC; elevated serum and fetal brain cytokine levels; altered frontal synaptophysin expression; reduced parvalbumin-expressing neurons in the hippocampus; down regulated expression of several genes involved in neurogenesis and neuronal migration; (direction of some changes are age-dependent)
Response to APD:	PPI deficit and elevated serum cytokines both reversed by haloperidol
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