Animal Model:	Rat Placental Insufficiency/Birth Insults
Preparation Type:	Developmental Preparations
DA-related behavior:	Enhanced amphetamine-induced locomotion and accumbal dopamine release
Gating:	Disrupted PPI (post-pubertal onset)
Cognitive behavior:	Performance on Morris water maze and T-maze appears normal
Molecular/morphological signature:	Reduced DA release in PFC, increased DAT in NAc (basal), decreased DA receptor expression; reduced dentate granule cells; region- and age-specific alterations in dendritic spine development; altered expression of presynaptic genes; decreased caudate-putamen volume
Response to APD:	PPI deficits reversed by clozapine
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