Animal Model:	Rat Antimitotic Agent – MAM or AraC
Preparation Type:	Developmental Preparations
DA-related behavior:	Enhanced response to amphetamine and MK-801 (post-puberty)
Gating:	Disrupted PPI (post-puberty)
Cognitive behavior:	Learning deficits in Morris water maze, object recognition, and attentional set-shifting; no change in 5-choice serial reaction time task
Social behavior:	Decreased social interaction (deficit present prior to puberty)
Molecular/morphological signature:	Reduced hippocampal volume; alterations of NMDAR protein levels and function in the hippocampus; increased neuron density in prefrontal cortex; enhanced NAc DA release to amphetamine; increased firing of dopaminergic neurons; enlarged lateral and third ventricles
Response to APD:	Increased response to MK-801 was attenuated by risperidone, haloperidol, and clozapine
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