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Important Notice: The Forum does not endorse any medical
product or therapy. ALL medications and supplements
should be taken ONLY under the supervision of a physician,
due to the possibility of side-effects, drug interactions,
etc.
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Animal Model:
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Basolateral Amygdala Picrotoxin Infusion-Rat
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Preparation Type:
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Drug-Induced Preparations
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Response to APD:
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GABA antagonism in BLA decreases GAD67 in HPC,
GABA antagonism in BLA increases HPC LTP
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Citations:
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Berretta S, Munno DW, Benes FM. Amygdalar activation alters
the hippocampal GABA system: 'partial' modelling for
postmortem changes in schizophrenia. J Comp Neurol . 2001
Mar 5 ; 431(2):129-38. Abstract
Gisabella B, Bolshakov VY, Benes FM. Regulation of
synaptic plasticity in a schizophrenia model. Proc Natl Acad
Sci U S A . 2005 Sep 13 ; 102(37):13301-6. Abstract
Berretta S, Benes FM. A rat model for neural
circuitry abnormalities in schizophrenia. Nat Protoc . 2006
Jan 1 ; 1(2):833-9. Abstract
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