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Animal Models

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Animal Model: Basolateral Amygdala Picrotoxin Infusion-Rat
Preparation Type: Drug-Induced Preparations
Response to APD: GABA antagonism in BLA decreases GAD67 in HPC, GABA antagonism in BLA increases HPC LTP
Citations: Berretta S, Munno DW, Benes FM. Amygdalar activation alters the hippocampal GABA system: 'partial' modelling for postmortem changes in schizophrenia. J Comp Neurol . 2001 Mar 5 ; 431(2):129-38. Abstract

Gisabella B, Bolshakov VY, Benes FM. Regulation of synaptic plasticity in a schizophrenia model. Proc Natl Acad Sci U S A . 2005 Sep 13 ; 102(37):13301-6. Abstract

Berretta S, Benes FM. A rat model for neural circuitry abnormalities in schizophrenia. Nat Protoc . 2006 Jan 1 ; 1(2):833-9. Abstract


July 23, 2014
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See our recent webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.

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