Carter CJ.
eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia?Schizophr Bull.
2007 Nov 1
;
33(6):1343-53.
Pubmed Abstract
Supplementary information for this paper is posted on the Polygenic pathways website. This includes a listing of the environmental risk factors associated with bipolar disorder or schizophrenia, which is appended at the bottom of the gene tables for each condition. There is also a page related to the genes in the (eIF2-α kinase signaling network).
For schizophrenia, the environmental risk factors are nicely discussed at the (Schizophrenia.com website). The odds-ratios, as respectable as for any susceptibility gene, are derived from a review by Sullivan, 2005.
The recent interest in toxoplasmosis (see SRF Forum Discussion) also emphasizes the importance of environmental influences as risk factors for schizophrenia.
