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Demjaha A, Murray RM, McGuire PK, Kapur S, Howes OD. Dopamine Synthesis Capacity in Patients With Treatment-Resistant Schizophrenia. Am J Psychiatry. 2012 Oct 3 ; Pubmed Abstract

Comments on News and Primary Papers


Primary Papers: Dopamine Synthesis Capacity in Patients With Treatment-Resistant Schizophrenia.

Comment by:  Jeffrey Lieberman, SRF Advisor
Submitted 9 October 2012
Posted 9 October 2012
  I recommend this paper

This interesting result is consistent with prior work by Abi-Dargham and Laruelle, and with prevailing hypotheses. A question is whether the treatment-resistant patients represent a stable phenotype or evolved to this in the course of their illness. In this context, it would be useful to know where in the course of their illness the patients were, and whether they were previously treatment responsive or not.

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