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Lee SH, Decandia TR, Ripke S, Yang J, , , , Sullivan PF, Goddard ME, Keller MC, Visscher PM, Wray NR. Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat Genet. 2012 Mar ; 44(3):247-50. Pubmed Abstract
Comments on News and Primary Papers
Primary Papers: Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

Comment by:  Bryan Roth, SRF Advisor
Submitted 24 February 2012 Posted 27 February 2012
  I recommend this paper

This is an interesting analytic paper which tests the hypothesis that common genomic variants are responsible for a substantial proportion of the variance in genomewide association studies of schizophrenia.

As large-scale efforts to fully sequence genomes of individuals with schizophrenia are underway at many centers, it will be interesting to revisit this hypothesis.

View all comments by Bryan Roth