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	Annotation


	Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton AA, Sacktor TC. Storage of spatial information by the maintenance mechanism of LTP. Science . 2006 Aug 25 ; 313(5790):1141-4. PubMed Abstract


	Comments on Paper and Primary News


	Primary News: Immune Receptor Controls Synaptic Plasticity; LTP Makes Memories Comment by: Avi Peled
	Submitted 29 September 2006	Posted 29 September 2006
	The relevance of synaptic plasticity to schizophrenia has been mentioned in this work and in many others. However, the mechanisms of neuronal plasticity have not been used to conceptualize a theoretical framework suggesting exactly in what way it is relevant to the development and maintenance of mental disorders. I have recently published two theoretical papers toward this goal, attempting furthermore to show its relevancy to a novel psychiatric diagnosis. See also www.brainoptimizers.org. References: Peled A. Brain profiling and clinical neuroscience. Medical Hypothesis 2006 May 12; [Epub ahead of print] Abstract Peled A. Plasticity imbalance in mental disorders the neuroscience of psychiatry: Implications for diagnosis and research. Medical Hypothesis 2005 July 1. Abstract View all comments by Avi Peled

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PRIMARY NEWS
Immune Receptor Controls Synaptic Plasticity; LTP Makes Memories