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Patients with schizophrenia have a reduced neural response to both unpredictable and predictable primary reinforcers.

Waltz JA, Schweitzer JB, Gold JM, Kurup PK, Ross TJ, Salmeron BJo, Rose EJane, McClure SM, Stein EA
Neuropsychopharmacology. 2009 May; 34(6):1567-77. PMID: 19052540. Pubmed