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News Brief: RAISE Study Supports Better Early Psychosis Treatment

19 Oct 2015

October 20, 2015. The primary outcome data from the Recovery After an Initial Schizophrenia Episode (RAISE) study support the use of more comprehensive, specialty care for people in the early stages of schizophrenia. As reported by SRF earlier this year (see SRF related news report), the RAISE data show that programs such as those validated in other countries from Australia to Europe can make a difference for many patients in the early stages of their illness, decreasing isolation from their normal school, work, and social lives, and hopefully improving outcomes.

The study was published October 20 in the American Journal of Psychiatry.

In an interview with The New York Times, lead investigator John Kane of Zucker Hillside Hospital in Glen Oaks, New York, indicated that in addition to the improvements in self-reported quality of life and school/work engagement reported in the paper, participants in the RAISE program were able to use significantly less antipsychotic medication.—Hakon Heimer.


Kane JM, Robinson DG, Schooler NR, Mueser KT, Penn DL, Rosenheck RA, Addington J, Brunette MF, Correll CU, Estroff SE, Marcy P, Robinson J, Meyer-Kalos PS, Gottlieb JD, Glynn SM, Lynde DW, Pipes R, Kurian BT, Miller AL, Azrin ST, Goldstein AB, Severe JB, Lin H, Sint KJ, John M, Heinssen RK. Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program. Am J Psychiatry. 2015 Oct 20. Abstract