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Bigger Schizophrenia GWAS Reports More Than 100 Hits
21 July 2014. A highly anticipated schizophrenia genome-wide association study published July 21 in Nature identifies 83 novel risk markers and replicates 25 others...

Dopamine dysfunction triggers massive reprogramming of cortex
21 July 2014. A malfunctioning dopamine system can lower expression of nearly 2000 genes in prefrontal cortex neurons...

Evidence Mounts for the Maternal Inflammation Hypothesis of Schizophrenia
15 July 2014. New data from a Finnish birth cohort link higher serum levels of the maternal inflammatory marker C-reactive protein during pregnancy to an elevated risk of schizophrenia in offspring...

15q11.2 Deletions Point to Cytoskeleton, Altered Migration in Schizophrenia
14 July 2014. Stem cells derived from people with schizophrenia carrying 15q11.2 deletions reveal structural problems that could result in misplaced neurons in the brain...

News Brief: Paul Patterson Dies
8 July 2014. Paul Patterson, well known to many SRF readers for his work at the interface of the nervous and immune systems, died June 25, 2014, at the age of 70...

SIRS 2014—Boosting Dopamine D1 Receptor Activity
8 July 2014. A SIRS 2014 session titled put the dopamine D1 receptor in the spotlight...

SIRS 2014—Schizophren–omics: Part 2
7 July 2014. The audience at the Schizophrenia International Research Society meeting returned for round two of the April 6, 2014, opening plenary session...

SIRS 2014—Schizophren–omics: Part 1
7 July 2014. Genomics, connectomics, proteomics, methylomics, transcriptomics—“There are many -omics that are now in our scientific dictionary,” said moderator Lynn DeLisi...

Schizophrenia Looms Large in International 22q11.2 Deletion Survey
3 July 2014. The largest survey to date of people with 22q11.2 deletions found that schizophrenia spectrum disorders afflicted 41 percent of those 25 and older...

Genetic Risk for Schizophrenia, Cannabis Use Overlap
30 June 2014. Genetic variants that increase risk for schizophrenia also increase the chance that a person will use cannabis...

Cortical Connection Linked to Genes Suspected in Schizophrenia
26 June 2014. Genes suspected in schizophrenia impinge upon a specific connection in the brain...

ANK3 Regulates Neuron Proliferation
13 June 2014. Ankyrin-G, the protein product of the gene ANK3 that has been linked to bipolar disorder and schizophrenia, has a hand in regulating the birth of new neurons in the developing brain...

Up Close and Exciting: The NMDA Glutamate Receptor
11 June 2014. One of several types of ligand-gated ion channel, the N-methyl-D-aspartate (NMDA) receptor transmits excitatory stimuli in the brain...

22q11DS Model Suggests Substrate for Auditory Hallucinations
5 June 2014. Disrupted connections between the thalamus and auditory cortex are found in a mouse model of 22q11DS, a strong genetic risk factor for schizophrenia...

SIRS 2014: Reports From Schizophrenia Clinical Drug Trials
3 June 2014. Several sessions at the SIRS 2014 meeting discussed data from clinical trials testing novel antipsychotics and a variety of other drugs...

Synaptic Metropolis—Microscopic Census Documents 300,000 Protein Inhabitants
2 June 2014. Wielding a combination of imaging and quantification techniques, researchers have generated the most detailed three-dimensional map of the synapse to date...

SIRS 2014: Refining Schizophrenia Clinical Drug Trials
2 June 2014. Speakers from academia and industry discussed lessons learned from past failed clinical trials and ways to improve those of the future...

News Brief: Elevated NMDA Receptor Antibodies in Schizophrenia Overturned
29 May 2014. A May 28 letter published online in JAMA Psychiatry reports no statistical difference between patients and controls...

Double Hit for Chromatin Remodeling in Schizophrenia Exomes
27 May 2014. The latest exome sequencing findings in schizophrenia cast suspicion upon SETD1A, a gene involved in chromatin remodeling...

News Brief: Long-Acting Forms of First- and Second-Generation Antipsychotics Go Head to Head
21 May 2014. Recent clinical trials such as CATIE have raised doubts about the advantages of oral forms of second-generation antipsychotics over their earlier counterparts...

NIH to Ensure Equal Study of Sexes in Preclinical Research
20 May 2014. The National Institutes of Health (NIH) has announced policies to ensure that males and females receive equal representation in preclinical research...

Exome Sequencing Highlights Chromatin Remodeling in Schizophrenia
19 May 2014. People with schizophrenia carry 3.5 times more spontaneously occurring point mutations than healthy controls do...

Interneuron Transplants Quell Overactivity in Hippocampus
15 May 2014. Weakened inhibition in the hippocampus can lead to brain overactivity similar to that found in schizophrenia...

SIRS 2014: Epidemiology Digs Deeper Into the Infection-Psychosis Link
13 May 2014. The immune system is again gaining attention in the etiology of schizophrenia and other psychotic disorders...

Sodium Channel Linked to Cognition in Schizophrenia
7 May 2014. Genetic variation in the sodium channel gene SCN2A contributes to cognition in people with schizophrenia...

1 to 25 of 804 results

See our recent webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.

Check out our Schizophrenia Bulletin Forum Discussion: Prefrontal Inefficiency Is Associated With Polygenic Risk for Schizophrenia.
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