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ICOSR 2015—Approaches to Prevention in Schizophrenia
24 April 2015. A number of presentations at the 2015 ICOSR addressed potential strategies for prevention in schizophrenia...


ICOSR 2015—Patient-Derived Cells For Schizophrenia Research
24 April 2015. The overall goal of this session was to investigate molecular mechanisms of schizophrenia using either patient-derived cells or animal models...


ICOSR 2015—Neuroinflammation, White Matter, and Schizophrenia
20 April 2015. Accumulating evidence suggests a potential role for inflammation in the pathophysiology of schizophrenia...


MRS Study Finds Lower GABA Levels in Older People With Schizophrenia
17 April 2015. The largest MRS study of GABA levels in schizophrenia reports that levels of the neurotransmitter are reduced in older people with schizophrenia compared to age-matched controls...


ICOSR 2015—Boosting Social Cognition in Schizophrenia
15 April 2015. Among the symptoms of schizophrenia, impairments in social cognition may cause the most disability and loss of quality of life...


ICOSR 2015—Higher Fruits From Gene-Gene Interactions?
7 April 2015. Adding risk SNPs together amounts to more substantial increases in schizophrenia risk, but strains to account for the disorder's heritability...


New Role for DISC1 in mRNA Transport
7 April 2015. The scaffolding protein disrupted in schizophrenia 1 (DISC1) plays a role in mRNA transport by acting as an RNA-binding protein...

  
ICOSR 2015—Schizophrenia Researchers Peek at RNA-seq
3 April 2015. The genetic clues found in the latest genomewide association study (GWAS) of schizophrenia mostly lie in non-coding regions of the genome...


ICOSR 2015—Stress and Glutamate Kick Off Rocky Mountain Congress
2 April 2015. Against a mountainous backdrop, nearly 1,000 schizophrenia researchers delved into the science of the 15th International Congress of Schizophrenia Research...


New Journal on the Schizophrenia Landscape
25 March 2015. npj Schizophrenia represents the first fully open-access, exclusively online generalist journal for the psychosis research field...

  
RAISE Study Supports Value of Early, Coordinated Schizophrenia Care
11 March 2015. Comprehensive early treatment and support can improve some outcomes in people with schizophrenia...

  
Linking Interneurons, Oscillations, and Cognition in Schizophrenia
10 March 2015. Three new mouse studies take a deeper look at the connection between PV interneurons and cognition...


PET Imaging Confirms Low Cortical Dopamine in Schizophrenia
4 March 2015. The first in vivo measure of cortical dopamine release in schizophrenia substantiates the long-suspected reduction of the neurotransmitter in the prefrontal cortex...


Cortical Changes and Medication Effects in Early Schizophrenia
24 February 2015. Two new studies provide insights into the structural and functional abnormalities found in the prefrontal cortex of people who have recently been diagnosed with schizophrenia...


Mental Illnesses Share Common Brain Changes
10 February 2015. Researchers have identified a trio of brain regions that come up smaller than normal across six mental illnesses...

  
In Fruit Flies, MicroRNA Protects Synapses Against Excitotoxicity
10 February 2015. With their ability to quickly fine-tune gene expression, microRNAs are a natural fit to regulate synaptic activity in response to the changing needs of the nervous system...


Spontaneous Gamma Power Higher in Schizophrenia
3 February 2015. A recent study reports that people with schizophrenia have increased spontaneous brain activity in the gamma range, mirroring findings from animal models of the disorder...


"Agnostic" RNA Analysis Shows Developmental Transcriptome Changes
3 February 2015. A new approach to the analysis of RNA-sequencing data reveals the most complete set of changes in transcriptional regulation across the lifespan identified to date...


Common Pathways Found for Some Psychiatric Disorders
29 January 2015. Diverse genetic clues associated with three psychiatric disorders, including schizophrenia, point to a subset of key biological processes...

  
Elusive Hybrid Dopamine Receptor Stirs Controversy
15 January 2015. The hybrid dopamine receptor consisting of D1 and D2 subunits may not matter much to normal brain function...

  
SfN 2014—Redox Dysregulation in Schizophrenia
13 January 2015. Data suggest that redox dysregulation interacts with glutamatergic dysfunction and neuroinflammation to cause cognitive and affective symptoms of schizophrenia...


SfN 2014—Glutamatergic Abnormalities Poster Tour
9 January 2015. The glutamate hypothesis of schizophrenia continues to be one of the field's most researched...


ErbB4 Tunes Attention in Thalamus
5 January 2015. A molecular suspect for schizophrenia may fine tune the brain's attention systems...


Disrupt DISC1-D2 Receptor Complex for Fewer Antipsychotic Side Effects?
22 December 2014. The scaffolding protein DISC1 interacts with the dopamine D2 receptor to form a complex...


Psychosis Risk Variant Linked to Enhanced Calcium Currents
12 December 2014. A common genetic variant linked to schizophrenia and bipolar disorder leaves a clear mark on calcium channels in neurons...


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SRF will be covering the International Congress on Schizophrenia Research, March 29-April 1, 2015. Look for reports on the sessions.
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