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1 to 25 of 853 results
PET Imaging Confirms Low Cortical Dopamine in Schizophrenia
4 March 2015. The first in vivo measure of cortical dopamine release in schizophrenia substantiates the long-suspected reduction of the neurotransmitter in the prefrontal cortex...


Cortical Changes and Medication Effects in Early Schizophrenia
24 February 2015. Two new studies provide insights into the structural and functional abnormalities found in the prefrontal cortex of people who have recently been diagnosed with schizophrenia...


Mental Illnesses Share Common Brain Changes
10 February 2015. Researchers have identified a trio of brain regions that come up smaller than normal across six mental illnesses...

  
In Fruit Flies, MicroRNA Protects Synapses Against Excitotoxicity
10 February 2015. With their ability to quickly fine-tune gene expression, microRNAs are a natural fit to regulate synaptic activity in response to the changing needs of the nervous system...


Spontaneous Gamma Power Higher in Schizophrenia
3 February 2015. A recent study reports that people with schizophrenia have increased spontaneous brain activity in the gamma range, mirroring findings from animal models of the disorder...


"Agnostic" RNA Analysis Shows Developmental Transcriptome Changes
3 February 2015. A new approach to the analysis of RNA-sequencing data reveals the most complete set of changes in transcriptional regulation across the lifespan identified to date...


Common Pathways Found for Some Psychiatric Disorders
29 January 2015. Diverse genetic clues associated with three psychiatric disorders, including schizophrenia, point to a subset of key biological processes...

  
Elusive Hybrid Dopamine Receptor Stirs Controversy
15 January 2015. The hybrid dopamine receptor consisting of D1 and D2 subunits may not matter much to normal brain function...

  
SfN 2014—Redox Dysregulation in Schizophrenia
13 January 2015. Data suggest that redox dysregulation interacts with glutamatergic dysfunction and neuroinflammation to cause cognitive and affective symptoms of schizophrenia...


SfN 2014—Glutamatergic Abnormalities Poster Tour
9 January 2015. The glutamate hypothesis of schizophrenia continues to be one of the field's most researched...


ErbB4 Tunes Attention in Thalamus
5 January 2015. A molecular suspect for schizophrenia may fine tune the brain's attention systems...


Disrupt DISC1-D2 Receptor Complex for Fewer Antipsychotic Side Effects?
22 December 2014. The scaffolding protein DISC1 interacts with the dopamine D2 receptor to form a complex...


Psychosis Risk Variant Linked to Enhanced Calcium Currents
12 December 2014. A common genetic variant linked to schizophrenia and bipolar disorder leaves a clear mark on calcium channels in neurons...


SfN 2014—Biomarkers in Psychotic Disorders
9 December 2014. Participants at SfN heard the latest EEG and MRI studies, along with a smattering of cellular research, in schizophrenia and bipolar disorder...

  
PIP 2014—Pharmacogenetics in Psychiatry
8 December 2014. This meeting included four sessions, with 12 oral presentations delivered on current topics of interest in the field, followed by a poster session...


Psychotic Symptoms in Young People Portend Later Problems
2 December 2014. Two-thirds of young people identified as being at very high risk of developing psychosis do not go on to develop a psychotic disorder within three years...


SfN 2014—Failure to Replicate Goes Under the Microscope
2 December 2014. Scientists at the 2014 Society for Neuroscience meeting discussed the lack of reproducibility of research studies...


IQ Study Finds Environmental Footprint in Schizophrenia Risk
26 November 2014. A study of over one million men reports that the long-standing association between cognitive ability and schizophrenia may stem from environmental factors...


Baseline Symptom Severity Affects Antipsychotic Response
17 November 2014. Patients with schizophrenia who are more severely affected reap more benefit from drug treatment than those whose baseline symptoms are more mild...

  
Corticostriatal Connectivity Predicts Antipsychotic Response
14 November 2014. The answer to whether an antipsychotic drug will relieve a person's hallucinations and delusions may be embedded within the brain's connections...

  
The Life of the Spine: Do Gene Knockdowns Add Insight Into Schizophrenia?
4 November 2014. Dendritic spine structure and function are controlled in part by two familiar genes...


WCPG 2014—Movement on MHC and Schizophrenia Risk
31 October 2014. The strongest and most replicable genetic signal for schizophrenia emanates from a region of chromosome 6...


WCPG 2014—Phenotypes and Families in Mind
30 October 2014. Rare variants revealed by sequencing have compelled researchers to get “back to basics” by analyzing family pedigrees...


WCPG 2014—Smoothing the Way to the Clinic
24 October 2014. Even as researchers gain traction on the genes involved in schizophrenia, turning these discoveries into clinically actionable information faces plenty of challenges...


Unpacking the "Placebo Problem" in Antipsychotic Drug Trials
21 October 2014. A large meta-analysis identifies factors to blame for the troubling increase in placebo response...


1 to 25 of 853 results

See our latest webinar, Cognition and Treatment Resistance in Schizophrenia, held November 10, 2014.

See our last webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.
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