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Elusive Hybrid Dopamine Receptor Stirs Controversy
15 January 2015. The hybrid dopamine receptor consisting of D1 and D2 subunits may not matter much to normal brain function...

SfN 2014—Redox Dysregulation in Schizophrenia
13 January 2015. Data suggest that redox dysregulation interacts with glutamatergic dysfunction and neuroinflammation to cause cognitive and affective symptoms of schizophrenia...

SfN 2014—Glutamatergic Abnormalities Poster Tour
9 January 2015. The glutamate hypothesis of schizophrenia continues to be one of the field's most researched...

ErbB4 Tunes Attention in Thalamus
5 January 2015. A molecular suspect for schizophrenia may fine tune the brain's attention systems...

Disrupt DISC1-D2 Receptor Complex for Fewer Antipsychotic Side Effects?
22 December 2014. The scaffolding protein DISC1 interacts with the dopamine D2 receptor to form a complex...

Psychosis Risk Variant Linked to Enhanced Calcium Currents
12 December 2014. A common genetic variant linked to schizophrenia and bipolar disorder leaves a clear mark on calcium channels in neurons...

SfN 2014—Biomarkers in Psychotic Disorders
9 December 2014. Participants at SfN heard the latest EEG and MRI studies, along with a smattering of cellular research, in schizophrenia and bipolar disorder...

PIP 2014—Pharmacogenetics in Psychiatry
8 December 2014. This meeting included four sessions, with 12 oral presentations delivered on current topics of interest in the field, followed by a poster session...

Psychotic Symptoms in Young People Portend Later Problems
2 December 2014. Two-thirds of young people identified as being at very high risk of developing psychosis do not go on to develop a psychotic disorder within three years...

SfN 2014—Failure to Replicate Goes Under the Microscope
2 December 2014. Scientists at the 2014 Society for Neuroscience meeting discussed the lack of reproducibility of research studies...

IQ Study Finds Environmental Footprint in Schizophrenia Risk
26 November 2014. A study of over one million men reports that the long-standing association between cognitive ability and schizophrenia may stem from environmental factors...

Baseline Symptom Severity Affects Antipsychotic Response
17 November 2014. Patients with schizophrenia who are more severely affected reap more benefit from drug treatment than those whose baseline symptoms are more mild...

Corticostriatal Connectivity Predicts Antipsychotic Response
14 November 2014. The answer to whether an antipsychotic drug will relieve a person's hallucinations and delusions may be embedded within the brain's connections...

The Life of the Spine: Do Gene Knockdowns Add Insight Into Schizophrenia?
4 November 2014. Dendritic spine structure and function are controlled in part by two familiar genes...

WCPG 2014—Movement on MHC and Schizophrenia Risk
31 October 2014. The strongest and most replicable genetic signal for schizophrenia emanates from a region of chromosome 6...

WCPG 2014—Phenotypes and Families in Mind
30 October 2014. Rare variants revealed by sequencing have compelled researchers to get “back to basics” by analyzing family pedigrees...

WCPG 2014—Smoothing the Way to the Clinic
24 October 2014. Even as researchers gain traction on the genes involved in schizophrenia, turning these discoveries into clinically actionable information faces plenty of challenges...

Unpacking the "Placebo Problem" in Antipsychotic Drug Trials
21 October 2014. A large meta-analysis identifies factors to blame for the troubling increase in placebo response...

News Brief: What Can CRISPR Do for You?
20 October 2014. Last year, the method took the molecular biomedical world by storm...

WCPG 2014—Stem Cells Gather Steam
17 October 2014. A session devoted to induced pluripotent stem cells (iPSCs) for modeling neuropsychiatric disease marked "a new era in psychiatric genetics,"...

WCPG 2014—Genomics Smorgasbord: Varied Samplings for Schizophrenia
16 October 2014. The 25th annual World Congress of Psychiatric Genetics got underway in Copenhagen, Denmark, on October 11...

Working Memory Deficit Hampers Reinforcement Learning in Schizophrenia
14 October 2014. The cognitive impairments in schizophrenia may be more tangled than previously appreciated...

What Can Hearing Loss Tell Us About Social Defeat, Dopamine Sensitization, and Schizophrenia?
10 October 2014. Like people with schizophrenia, those with severe hearing impairment show increased dopamine hypersensitivity in the striatum...

GABA and Glutamate Co-release Appears to Titrate Depression
9 October 2014. Axon terminals that release not one, but both, of the major neurotransmitters may tilt a brain toward or away from depression...

Blood Test Predicts Conversion to Psychosis in Preliminary Study
8 October 2014. A panel of blood markers related to stress reactivity, inflammation, and oxidative stress can be used to help predict which high-risk subjects will develop psychosis...

1 to 25 of 846 results

See our latest webinar, Cognition and Treatment Resistance in Schizophrenia, held November 10, 2014.

See our last webinar, Research Domain Criteria (RDoC) Applied to Verbal Hallucinations, held May 28, 2014.
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