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Deviation From Family Cognitive Aptitude May Help Predict Schizophrenia Risk
19 April 2016. A new study shows a person's poor cognitive performance relative to his or her family members is associated with a higher risk of developing schizophrenia....

FDA Advisory Committee Recommends Pimavanserin for Parkinson's Disease Psychosis
19 April 2016. An FDA advisory committee recommended that pimavanserin (trade name Nuplazid®) be approved for treating Parkinson's disease psychosis...

SIRS 2016—Of Vitamin D, Critical Periods, and Clinical Trials
14 April 2016. John McGrath of Queensland Brain Institute in Brisbane, Australia, deftly bridged the gap between epidemiology and neuroscience....

SIRS 2016—Tracing Trajectories in Longitudinal Studies
13 April 2016. Plenary speaker Raquel Gur argued that getting a better idea of the earliest stages of risk for mental illness is essential for precision medicine....

SIRS 2016—Subtyping Schizophrenia
8 April 2016. Considering the heterogeneity of schizophrenia, researchers have been looking for signs beyond symptoms that may divide the diagnosis into more homogeneous subgroups...

SIRS 2016—A New Day for Dopamine?
5 April 2016. The study of dopamine dysfunction, once the dominant theme in schizophrenia research, has faded a bit in recent years...

SIRS 2016—Florence Warmly Welcomes Schizophrenia Researchers
4 April 2016. The Fifth Schizophrenia International Research Society (SIRS) conference got underway in balmy Florence, Italy, on Saturday evening, April 2....

Encenicline Misses Endpoints in Two Phase 3 Schizophrenia Trials
29 March 2016. FORUM Pharmaceuticals announced topline results yesterday of its experimental drug encenicline...

Studies Converge on SETD1A as Schizophrenia Risk Gene
23 March 2016. Two studies have converged on the same gene, SETD1A, as a major risk factor for schizophrenia....

Molecular Magneto: Protein Opens Neuronal Ion Channel as Commanded by Magnetic Field
22 March 2016. Scientists have invented a protein, Magneto (of X-Men fame), that allows them to use a magnetic field to control the firing of neurons...

New Study Finds Schizophrenia Risk Gene TCF4 Regulates Neuronal Excitability
16 March 2016. A new study provides insights into how a schizophrenia risk gene regulates the excitability of neurons in the rodent prefrontal cortex...

News Brief: NIMH Budget and Director Search
9 March 2016. There is such a thing as good budget news...

New Study Shows Nonrandom Mating in People With Psychiatric Disorders
4 March 2016. Results from a new study show that people with psychiatric disorders pair with partners who also have a psychiatric disorder more frequently than would be expected by chance...

Deletion Model Adds to Understanding of Genes-to-Behavior Pathways
26 February 2016. Two papers highlight the power of the 22q11.2 deletion mouse model to reveal the genetic and molecular underpinnings of these diverse impairments...

New Compounds May Help Probe the Glutamate Hypothesis of Schizophrenia
19 February 2016. Newly discovered compounds that can modulate particular NMDA receptors may help researchers explore the etiology of schizophrenia...

Early Psychosis Research Matures, Going Both Deep and Wide
15 February 2016. The turmoil of a first psychotic episode suggests major changes in brain function, yet the beginnings of a break from reality remain mysterious...

Genetic Variants Tied to Lithium Response in Bipolar Disorder
15 February 2016. In a large GWAS of drug response in a psychiatric disease, investigators have identified variants connected with the therapeutic effects of lithium in bipolar disorder...

News Briefs: RAISE Cost-Effectiveness and Clozapine in Treatment-Resistant Schizophrenia
9 February 2016. The benefits of comprehensive treatment for first-episode psychosis outweigh its higher costs, and a study suggests clozapine is no more effective than most other drugs...

Will Death in French Drug Trial Lead to Tighter Phase 1 Rules?
8 February 2016. This month saw one of the worst drug trial debacles in memory...

Purification of Adult Human Astrocytes Shows: They Are Unique
29 January 2016. Astrocytes make up almost half of a person's brain cells and are increasingly recognized to play a role in neurodegenerative disease...

C4 Genes Tune Schizophrenia Risk, Synaptic Pruning
28 January 2016. Variations in a gene known for its role in immune function may increase a person's risk of schizophrenia by influencing synaptic pruning during brain development...

The Schizophrenia Research Community Remembers Connie Lieber
25 January 2016. Connie Lieber, philanthropist and advocate for the mentally ill, passed away on January 15, 2016....

Will Biotypes Redefine Psychosis Research?
15 January 2016. A panel of laboratory tests that assesses brain function can divide people with psychotic disorders into distinct clusters that do not respect the standard diagnoses...

Psychiatric Research Philanthropist Ted Stanley Dies at 84
14 January 2016. Philanthropist Ted Stanley died on January 3 at the age of 84...

Game Over? Federal Trade Commission Calls Brain-Training Claims Inflated
12 January 2016. Brain-training software has become big business, but now regulators are stepping in to rein in the advertising...

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