Schizophrenia Research Forum - A Catalyst for Creative Thinking
Home Profile Membership/Get Newsletter Log In Contact Us
 For Patients & Families
What's New
Recent Updates
SRF Papers
Current Papers
Search All Papers
Search Comments
Research News
Conference News
Plain English
Current Hypotheses
Idea Lab
Online Discussions
Virtual Conferences
What We Know
Animal Models
Drugs in Trials
Research Tools
Community Calendar
General Information
Member Directory
Researcher Profiles
Institutes and Labs
About the Site
SRF Team
Advisory Board
Support Us
How to Cite
Fan (E)Mail
The Schizophrenia Research Forum web site is sponsored by the Brain and Behavior Research Foundation and was created with funding from the U.S. National Institute of Mental Health.
Research News
back to News Search
News Update: What Does CATIE Mean for Treatment?

26 January 2006. In the December issue of the journal Psychiatric Services, Mark Ragins, of Village Integrated Services Agency in Long Beach, California, wrote an editorial on the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) report in the September 19, 2005, issue of the New England Journal of Medicine (see SRF related news story and commentary). He suggested that the high drug discontinuation rates reflected problems with the treatment the patients received while in the study, and concluded, "I don't think the CATIE study should be a wake-up call to 'clinicians, patients, families, and policymakers.' I think it should be a wake-up call to researchers." In the January issue of Psychiatric Services, study authors Jeff Lieberman of Columbia University and John Hsiao of the National Institute of Mental Health respond to Ragins's letter, explaining aspects of the study protocol and conclusions, and pointing out that the New England Journal of Medicine report "is but an initial installment from a remarkably rich data set." (See, e.g., Goff et al., 2005; Miller et al., 2005; McEvoy et al., 2005; and Meyer et al., 2005). Access to both of these articles in Psychiatric Services is free.—Hakon Heimer.

Ragins M. Should the CATIE study be a wake-up call? Psychiatr Serv. 2005 Dec 1;56(12):1489. Abstract

Lieberman JA, Hsiao JK. Interpreting the Results of the CATIE Study. Psychiatr Serv. 2006 Jan 1;57(1):139. Abstract

Comments on News and Primary Papers
Primary Papers: Interpreting the Results of the CATIE Study.

Comment by:  Patricia Estani
Submitted 4 February 2006 Posted 6 February 2006
  I recommend this paper

In the comment about the CATIE study, Dr. Ragins described...  Read more

View all comments by Patricia Estani

Comment by:  Marvin Herz
Submitted 7 February 2006 Posted 8 February 2006

I believe that the results of the CATIE study indirectly...  Read more

View all comments by Marvin Herz
Comments on Related Papers
Related Paper: Cure therapeutics and strategic prevention: raising the bar for mental health research.

Comment by:  William Carpenter, SRF Advisor (Disclosure)
Submitted 17 January 2006 Posted 18 January 2006
  I recommend this paper

This perspective piece is right on target. Little progress...  Read more

View all comments by William Carpenter

Related Paper: Is quality of life among minimally symptomatic patients with schizophrenia better following withdrawal or continuation of antipsychotic treatment?

Comment by:  William Carpenter, SRF Advisor (Disclosure)
Submitted 22 January 2006 Posted 23 January 2006
  I recommend this paper

There are a number of studies suggesting that a subgroup...  Read more

View all comments by William Carpenter

Related Paper: Cure therapeutics and strategic prevention: raising the bar for mental health research.

Comment by:  Ed Francell
Submitted 24 January 2006 Posted 25 January 2006
  I recommend this paper

This article states very well the divergent approaches...  Read more

View all comments by Ed Francell
Submit a Comment on this News Article
Make a comment on this news article. 

If you already are a member, please login.
Not sure if you are a member? Search our member database.

*First Name  
*Last Name  
Country or Territory  
*Login Email Address  
*Confirm Email Address  
*Confirm Password  
Remember my Login and Password?  
Get SRF newsletter with recent commentary?  
Enter the code as it is shown below:
This code helps prevent automated registrations.

I recommend the Primary Papers

Please note: A member needs to be both registered and logged in to submit a comment.


(If coauthors exist for this comment, please enter their names and email addresses at the end of the comment.)


SRF News
SRF Comments
Text Size
Reset Text Size
Copyright © 2005- 2016 Schizophrenia Research Forum Privacy Policy Disclaimer Disclosure Copyright