Add your thoughts to a Forum Discussion on the dominant current hypothesis on the formation of delusions in schizophrenia, a discussion stimulated by recent articles in Cognitive Neuropsychiatry.
In this installment of our Forum "journal club" series, we join with Cognitive Neuropsychiatry to stimulate discussion of several recent articles in the journal. The articles under consideration can be accessed by clicking on the links to the left. We invite you to share your ideas and insights, questions, and reactions. So read on!
Oren Griffiths of the University of New South Wales in Sydney, Australia, and colleagues recently reviewed the hypothesized role of faulty prediction error mechanisms in leading to delusions in psychosis. In particular, they find limitations in the attempts by Philip Corlett of Yale University in New Haven, Connecticut, and Paul Fletcher of the University of Cambridge in the United Kingdom and their colleagues to test this experimentally in humans and to detect changes in neural activity using neuroimaging. Corlett and Fletcher wrote a detailed reply and we felt that these papers could serve as the basis for a useful update and discussion topic.
Cognitive Neuropsychiatry editor Anthony David and the publisher, Taylor and Francis, have kindly made these articles open access to facilitate this discussion, and as seed for the discussion, please read this initial comment by SRF member Guillermo Horga of Columbia University in New York City.