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The Extended Psychosis Phenotype

Posted on 4 Apr 2012
Jim van Os Ian Kelleher Irving Gottesman

Our April 5 Webinar, facilitated by Schizophrenia Bulletin and Oxford Press, featured talks by Jim van Os, presenting work from his group at the Maastricht University Medical Center, The Netherlands, and Ian Kelleher, presenting his work in Mary Cannon's group at the Royal College of Surgeons, Dublin, Ireland. Mystery guest Irving Gottesman of the University of Minnesota followed with a comment on the discussions.


If you missed the session, or just want to review it, click on the image below. In addition, you are still welcome to submit comments on either the background reading or any of the presentations. Gottesman also suggested the following citations as valuable background: Gottesman, 1987 and Str"mgren, 1994.

Courtesy of Schizophrenia Bulletin and Oxford Press, you can read an open-access introductory article to the theme by van Os and Richard Linscott.

The papers from the theme presented and discussed were:

van Os J, Linscott RJ. Introduction: the extended psychosis phenotype"relationship with schizophrenia and with ultrahigh risk status for psychosis. Schizophr Bull. 2012 Mar ;38(2):227-30. Abstract

Wigman JT, van Nierop M, Vollebergh WA, Lieb R, Beesdo-Baum K, Wittchen HU, van Os J. Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity--implications for diagnosis and ultra-high risk research. Schizophr Bull. 2012 Mar ;38(2):247-57. Abstract

van Nierop M, van Os J, Gunther N, Myin-Germeys I, de Graaf R, Ten Have M, van Dorsselaer S, Bak M, van Winkel R. Phenotypically Continuous With Clinical Psychosis, Discontinuous in Need for Care: Evidence for an Extended Psychosis Phenotype. Schizophr Bull. 2011 Sep 9; Abstract

Kelleher I, Murtagh A, Molloy C, Roddy S, Clarke MC, Harley M, Cannon M. Identification and Characterization of Prodromal Risk Syndromes in Young Adolescents in the Community: A Population-Based Clinical Interview Study. Schizophr Bull. 2011 Nov 17; Abstract

Listen to the Webinar
Click on this image to launch the recording.