 |
|
Researcher Profile - Aaron Marley |
 |
|
Neurodevelopmental disorders (e.g., 22q11 deletion syndromes), Schizophrenia
|
Microscopy, Molecular and Cell biology, Cell biology, Neurodevelopment, Protein structure/chemistry, Signal transduction
|
I work on how schizophrenia risk genes affect trafficking and signalling of GPCRs. |
DISC1 regulates primary cilia that display specific dopamine receptors.
Marley A, von Zastrow M. PLoS One. 2010 May 28;5(5):e10902.PMID: 20531939
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes.
Marley A, von Zastrow M.
PLoS One. 2010 Feb 19;5(2):e9325.PMID: 20174469
Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes.
Hislop JN, Marley A, Von Zastrow M.
J Biol Chem. 2004 May 21;279(21):22522-31. Epub 2004 Mar 15.PMID: 15024011 [PubMed - indexed for MEDLINE]Related articlesFree article
2.
Modulation of postendocytic sorting of G protein-coupled receptors.
Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M.
Science. 2002 Jul 26;297(5581):615-20.PMID: 12142540 [PubMed - indexed for MEDLINE]Related articlesFree article |
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis.
Dickman DK, Davis GW.
Science. 2009 Nov 20;326(5956):1127-30.PMID: 19965435 |
|
|
 |
|
 |