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Schizophrenia Research Forum: Researcher Profile - Shin-ichi Kano
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Researcher Profile - Shin-ichi Kano

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Member reports no financial or other potential conflicts of interest. [Last Modified: 2 April 2015]
View all comments by Shin-ichi Kano
Clinical Interests:
Bipolar disorder , Depression, Anxiety disorders , Neurodevelopmental disorders (e.g., 22q11 deletion syndromes), Drug abuse, Autism spectrum disorders (pervasive developmental disorders), Schizophrenia
Research Focus:
Immunology, Cell biology, Neuropathology, Neurotransmission, Proteomics, Glia/myelin, Glutamatergic transmission, Animal models, Molecular and Cell biology, Neurodevelopment, DNA microrrays, Pharmacology, Signal transduction, Stem cells
Work Sector(s):
Web Sites:
Top Papers
1: Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Tristan C, Kondo MA, Chen Y, Wilson A, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, Kato TA, Horiuchi Y Sedlak TW, Lee Y, Rapoport JL, Hirose S, Okano H, Valle D, O'Donnell, Sawa A, Kai M.
Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy.
Current Molecular Medicine. 2015. Mar 2.
PMID: 25732146

2: Kano S, Colantuoni C, Han F, Zhou Z, Yuan Q, Wilson A, Takayanagi Y, Lee Y, Rapoport J, Eaton W, Cascella N, Ji H, Goldman D, Sawa A
Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia.
Mol Psychiatry. 2013 Jul;18(7):740-2.
PMID: 22925834

3: Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A.
Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids.
Science. 2013 Jan 18;339(6117):335-9.
PMID: 23329051

4: Kano S, Nwulia E, Niwa M, Chen Y, Sawa A, Cascella N.
Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia.
Neurosci Res. 2011 Nov;71(3):289-93.
PMID: 21801761

5: Kano S, Sato K, Morishita Y, Vollstedt S, Kim S, Bishop K, Honda K, Kubo M, Taniguchi T.
The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells.
Nat Immunol. 2008 Jan;9(1):34-41. Epub 2007 Dec 2.
PMID: 18059273

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