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Schizophrenia Research Forum: Researcher Profile - Anthony Hannan
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Researcher Profile - Anthony Hannan

RESEARCHER INFORMATION
First Name:Anthony
Last Name:Hannan
Title:Assoc. Prof.
Advanced Degrees:PhD
Affiliation:University of Melbourne
Department:Howard Florey Institute
Street Address 1:Parkville
City:Melbourne
State/Province:VIC
Zip/Postal Code:3010
Country/Territory:Australia
Phone:+61 3 8344 7316
Fax:+61 3 9348 1707
Email Address: ajh@florey.edu.au
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 24 February 2008]
View all comments by Anthony Hannan
Clinical Interests:
Autism spectrum disorders (pervasive developmental disorders), Schizophrenia, Neurodevelopmental disorders (e.g., 22q11 deletion syndromes), Psychology, Depression
Research Focus:
Animal models, Molecular and Cell biology, Neuroanatomy/Systems Neuroscience, DNA microrrays, Pharmacology, Genetics, Stem cells, Brain imaging, Cell biology, Neurodevelopment, Neurotransmission, Proteomics, Signal transduction, Glutamatergic transmission
Work Sector(s):
Research institute
Web Sites:
Lab: http://www.florey.edu.au/research/scientific-laboratories/brain-development/neural-plasticity/
Top Papers
McOmish CE, Burrows E, Howard M, Scarr E, Kim D, Shin HS, Dean B, van den Buuse M, Hannan AJ. Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration. Mol Psychiatry. 2007 Jul 31; [Epub ahead of print] PMID: 17667964 [PubMed - as supplied by publisher]

McOmish CE, Hannan AJ. Enviromimetics: exploring gene environment interactions to identify therapeutic targets for brain disorders.
Expert Opin Ther Targets. 2007 Jul;11(7):899-913. Review. PMID: 17614759 [PubMed - indexed for MEDLINE]

Gray L, Hannan AJ.Dissecting cause and effect in the pathogenesis of psychiatric disorders: genes, environment and behaviour. Curr Mol Med. 2007 Aug;7(5):470-8. Review. PMID: 17691962 [PubMed - in process]

Nithianantharajah J, Hannan AJ. Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci. 2006 Sep;7(9):697-709. Review.
PMID: 16924259 [PubMed - indexed for MEDLINE]

Grote HE, Bull ND, Howard ML, van Dellen A, Blakemore C, Bartlett PF, Hannan
AJ. Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine. Eur J Neurosci. 2005 Oct;22(8):2081-8. PMID: 16262645 [PubMed - indexed for MEDLINE]

Mazarakis NK, Cybulska-Klosowicz A, Grote H, Pang T, Van Dellen A, Kossut M, Blakemore C, Hannan AJ. Deficits in experience-dependent cortical plasticity and sensory-discrimination
learning in presymptomatic Huntington's disease mice. J Neurosci. 2005 Mar 23;25(12):3059-66.
PMID: 15788762 [PubMed - indexed for MEDLINE]

Spires TL, Molnár Z, Kind PC, Cordery PM, Upton AL, Blakemore C, Hannan AJ. Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-beta1 signalling.
Cereb Cortex. 2005 Apr;15(4):385-93.
PMID: 15749982 [PubMed - indexed for MEDLINE]

Spires TL, Grote HE, Varshney NK, Cordery PM, van Dellen A, Blakemore C, Hannan AJ. Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.
J Neurosci. 2004 Mar 3;24(9):2270-6.
PMID: 14999077 [PubMed - indexed for MEDLINE]

Hannan AJ, Blakemore C, Katsnelson A, Vitalis T, Huber KM, Bear M, Roder J, et al. PLC-beta1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex. Nat Neurosci. 2001 Mar;4(3):282-8. PMID: 11224545 [PubMed - indexed for MEDLINE]

van Dellen A, Blakemore C, Deacon R, York D, Hannan AJ. Delaying the onset of Huntington's in mice. Nature. 2000 Apr 13;404(6779):721-2.



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