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Schizophrenia Research Forum: Researcher Profile - Tatiana Lipina
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Researcher Profile - Tatiana Lipina

RESEARCHER INFORMATION
First Name:Tatiana
Last Name:Lipina
Title:PhD
Affiliation:SLRI at Mount Sinai Hospital
Department:Center of CNS functions and neurodevelopment
Street Address 1:600 University Ave
City:Toronto
State/Province:Ontario
Zip/Postal Code:M5G 1X5
Country/Territory:Canada
Phone:416-586-8242
Email Address: lipina@mshri.on.ca
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 27 October 2006]
View all comments by Tatiana Lipina
Clinical Interests:
Schizophrenia
Research Focus:
Animal models, Immunology, Neurodevelopment, Pharmacology, Genetics, Glutamatergic transmission, Pharamacology
Work Sector(s):
Research institute
Web Sites:
Professional: http://www.mshri.on.ca/researchCentres.html
Lab: http://www.mshri.on.ca/roder/index.html
Reasearcher Bio
Current reserach interests:

Investigating of schizophrenia on gene-modified mice with focus on neurodevelopment

Search of relevant drug treatments for mouse mutants

Study of environment X genetic interactions
Top Papers
Lipina T, Weiss K, Roder J.
The Ampakine CX546 Restores the Prepulse Inhibition and Latent Inhibition Deficits in mGluR5-Deficient Mice. Neuropsychopharmacology. 2006 Aug 23

Lipina T, Labrie V, Weiner I, Roder J. Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. (Psychopharmacology 2005, Apr;179(1):54-67.

Avgustinovich DF, Lipina TV, Bondar NP, Alekseyenko OV, Kudryavtseva NN. Features of the genetically defined anxiety in mice. Behav Genet. 2000 Mar;30(2):101-109

Kudryavtseva NN. Lipina TV, Koryakina LA. Effects of haloperidol on communicative and aggressive behavior in male mice with different experiences of aggression. Pharmacol Biochem Behav. 1999 Jun; 63(2):229-236.

Avgustinovitch DF, Lipina TV, Alekseenko OV, Kudryavtseva NN. Changes in brain serotonergic activity in anxious losers. Biogenic Amines, 1999, v15 (4): 395-404




What are the top three papers (not yours) you have read recently?
Meyer U, Feldon J, Schedlowski M, Yee BK. "Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia."
Neurosci Biobehav Rev. 2005;29(6):913-47.

Nawa H, Takei N.
Recent progress in animal modeling of immune inflammatory processes in schizophrenia: implication of specific cytokines. Neurosci Res. 2006 Sep;56(1):2-13. Epub 2006 Jul 11

Hennah W, Thomson P, Peltonen L, Porteous D. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.
Schizophr Bull. 2006 Jul;32(3):409-16. Epub 2006 May 12

If resources were not limited, what research projects would you pursue?
complete list of genes which predispose organism to schizophrenia based on experiments with different types of environmental manipulations
What is your leading hypothesis?
Glutamatergic and neurodevelopmental



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