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Schizophrenia Research Forum: Researcher Profile - Scott Hemby
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Researcher Profile - Scott Hemby

RESEARCHER INFORMATION
First Name:Scott
Last Name:Hemby
Title:Professor
Advanced Degrees:PhD
Affiliation:Wake Forest University
Department:Physiology/Pharmacology
Street Address 1:Medical center Boulevard
City:Winston-Salem
State/Province:NC
Zip/Postal Code:27157
Country/Territory:U.S.A.
Phone:336-716-8620
Fax:336-716-8501
Email Address: 
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 15 October 2009]
View all comments by Scott Hemby
Clinical Interests:
Drug abuse, Depression, Schizophrenia
Research Focus:
Brain imaging, Neuropathology, Animal models, Molecular and Cell biology, DNA microrrays, Neurotransmission, Pharmacology, GABAergic transmission, Proteomics, Glutamatergic transmission
Work Sector(s):
University
Web Sites:
Lab: http://www1.wfubmc.edu/PhysPharm/faculty/hemby/
Top Papers
1. S.E. Hemby, W.Tang, and B. Horman (2005). Regulation of glutamate receptor subunits following cocaine self-administration. Brain Research, 1064:75-82.

2. S. E. Hemby, W. Tang, E.C. Muly, M.J. Kuhar, L. Howell, D.C. Mash (2005). Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of Neurochemistry, 95:1785-1793.

3. J.E. Smith, C. Co, M. Coller, S.E. Hemby and T.J. Martin (2006). Heroin potentates the reinforcing effects of cocaine and enhances the effects of cocaine on the extracellular fluid levels of nucleus accumbens dopamine. Neuropsychopharmacology, 31:139-150.
4. J. O’Connor, E.C. Muly, S.E. Hemby. (2006). Molecular mapping of striatal subregions in Macaca Mulata. Experimental Neurology, 198:326-337.

5. N. Tannu and S.E. Hemby (in press: Electrophoresis) Quantitation in two dimensional fluorescence difference gel electrophoresis (2DIGE): effect of protein fixation

6. J. O’Connor, W. Hasenkamp, B. Horman, E.C. Muly and S.E. Hemby (in press: Biological Psychiatry). Region specific regulation of NR1 subunit in rhesus monkeys following chronic antipsychotic drug administration.

7. S.E. Hemby, J.Q. Trojanowski, and S.D. Ginsberg (2003). Neuron specific age related decreases in dopamine receptor subtype mRNAs Journal of Comparative Neurology, 456: 176-183.

8. W. Tang, W. Fasulo, D. Mash, S. Hemby (2003). Molecular profiling of midbrain dopamine regions in cocaine overdose victims. Journal of Neurochemistry, 85: 911-924.

9. W.H. Fasulo and S.E. Hemby. (2003) Time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. Journal of Neurochemistry, 87: 205-219.

10. S.E. Hemby, S. Ginsberg, B. Brunk, S.E. Arnold, J.Q. Trojanowski, and J.H. Eberwine (2002) Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Archives of General Psychiatry, 59: 631-640.

What are the top three papers (not yours) you have read recently?
1. Akbarian S. Ruehl MG. Bliven E. Luiz LA. Peranelli AC. Baker SP. Roberts RC. Bunney WE Jr. Conley RC. Jones EG. Tamminga CA. Guo Y. Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Archives of General Psychiatry. 62(8):829-40, 2005.

2. Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Keefe RS, Davis SM, Davis CE, Lebowitz BD, Severe J, Hsiao JK, . Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med . 2005 Sep 22 ; 353(12):1209-23.
What is your leading hypothesis?
Glutamate



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