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Researcher Profile - Jonathan Burns |
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| First Name: | Jonathan | | Last Name: | Burns | | Title: | Dr | | Advanced Degrees: | FCPsych(SA); MSc(Edin) | | Affiliation: | Nelson Mandela School of Medicine, University of KwaZulu-Natal | | Department: | Department of Psychiatry | | Street Address 1: | Dept of Psychiatry, NRMSM | | City: | Durban | | State/Province: | KZN | | Zip/Postal Code: | 4000 | Country/Territory: | South Africa | | Phone: | -27-31-7656437 | | Fax: | -27-31-7656437 | | Email Address: |  |
Disclosure:
(view policy) |
Member reports no financial or other potential conflicts of interest. [Last Modified: 17 May 2006]
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View all comments by Jonathan Burns
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Psychology, Schizophrenia, Bipolar disorder
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Brain imaging, Neurodevelopment, Phenomenology/diagnosis, Animal models, Neuroanatomy/Systems Neuroscience, Neuropathology, Epidemiology, Genetics
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University, Medical hospital
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MRC Research Fellow 2001/2 for Prof Eve Johnstone, University of Edinburgh, conducted DTI in schiz research and worked on High Risk study.
Ongoing research on evolutionary origins of psychosis and the social brain.
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Burns, J.K. (2004) An evolutionary theory of schizophrenia: cortical connectivity, metarepresentation and the social brain. Behavioural and Brain Science Vol 27 (6): 831-55.
Burns, J.K. (2004) Elaborating the social brain hypothesis of schizophrenia. Behavioral and Brain Science Vol 27 (6): 68-86.
Burns J., Job D., Bastin M.E., Whalley H., MacGillivray T., Johnstone E.C., Lawrie S.M. (2003) Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study. The British Journal of Psychiatry 182: 439-443.
Burns, J.K. (2006) The social brain hypothesis of schizophrenia. World Psychiatry (In press).
Burns, J.K. (2006) Schizophrenia and brain evolution – Integrating the evidence. Progress in Neuro-Psychopharmacology & Biological Psychiatry (In press).
Burns, J.K. (2006) Neuronal Networks – evolutionary origins, developmental aberrations and psychopathology. In: F. Columbus (Ed.): New Research on Neuronal Networks Nova Science Publishers (In press).
McIntosh A.M., Holmes S., Gleeson S., Burns J.K., Hodges A.K., Byrne M.J., Dobbie R., Miller P., Lawrie S.M. and Johnstone E.C. (2002). Maternal recall bias, obstetric history and schizophrenia. The British Journal of Psychiatry 181: 520-525.
Marjoram, D., Gardner, C., Burns, J., Miller, P., Lawrie, S.M. & Johnstone, E.C. (2005) Symptomatology and social inference: A theory of mind study of schizophrenia and psychotic affective disorder. Cognitive Neuropsychiatry 10 (5) 347-59.
Burns, J. (2003)Book review: ‘The Speciation of Modern Homo sapiens’, Edited by Tim Crow, Oxford University Press, Oxford, 2002. In: The British Journal of Psychiatry 183: 82.
Burns, J. Book review: ‘The Social Brain: Evolution and Pathology’, Edited by Martin Brüne, Hedda Ribbert and Wulf Schiefenhövel, John Wiley & Sons Ltd, Chichester, 2003. In: The Human Ethology Bulletin (In press).
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Saha, S., Chant, D., Welham, J. and McGrath, J. (2005) A systmatic review of the prevalence of schizophrenia. PLoS Med 2(5): e141.
Kelly, B.D. (2005) Structural violence and schizophrenia. Social Science and Medicine 61: 721-30.
Arbib, M.A. and Mundhenk, T.N. (2005) Schizophrenia and the mirror system: an essay. Neuropsychologia 43: 268-80. |
Large epidemiological study of schizophrenia (preferably first-episode) in South Africa. I would want to look at socio-economic demographics as well as specific symptomatology in this 3rd world context. I would also like to follow a cohort of 1st episodes to determine course and outcome in this 3rd world context.
A collaboration with one or more other centres (possibly also 3rd world), following parallel study designs, would be highly desirable. |
I believe that the prevalence, course and outcome varies according to socioeconomic context. The obvious genetic basis to schizophrenia is expressed to a greater or lessor extent according to factors such as poverty, social deprivation and alienation. Schizophrenia is a disorder of social brain functioning, therefore social hardships worsen the expression of the disease and worsen outcome. |
Large population studies comparing prevalence, symtomatology, course and outcome that show:
a) that higher prevalence is associated with higher poverty markers, lower social capital and measures of greater social alienation.
b) Better course and outcome is associated with less deprivation, greater social capital and greater social inclusion. |
The heterogenous nature of this disorder means that we may never really unravel all the factors that mediate expression, course and outcome! |
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